Spiritborn Centipede Guide - Diablo 4: Builds & Skills

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Unlock the power of Spiritborn Centipede in Diablo 4 with unique skills and exciting build options for enhanced gameplay.

Spiritborn Centipede Guide

In this guide, we will explore the Spiritborn Centipede in Diablo 4, focusing on its playstyle, skills, and various build options available.


The Centipede is one of four spirit guardian creatures, alongside the Jaguar, Gorilla, and Eagle. These options are part of the Spiritborn class, introduced with the upcoming Vessel of Hatred expansion.


You can start designing your own Centipede builds by visiting the Diablo 4 build planner now!


For those familiar with the Druid class in Diablo 4, imagine Spirit Boons that are significantly enhanced. For newcomers, these spirits provide your character with robust passive abilities.


They offer unique skills that can boost attack speed for increased damage output, inflict damage over time through potent poisons, and even facilitate a pseudo-ranged combat style through the Spiritborn's capabilities.


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Harness the power of spirits to enhance your abilities in a unique way. When you choose the centipede spirit, all your skills gain a new “centipede” classification, similar to the way the claw skill is recognized as a “werewolf skill.”


One of the most intriguing features is the ability to wield two spirits simultaneously, which opens the door to extensive build customization, innovative combinations, and optimal gear setups. This creates an exciting environment for theory crafters to explore!


Siphon the life force from foes, converting their strength into your own! Utilize vicious toxins and debilitating effects to incapacitate your enemies, draining their vitality until they are nothing more than remnants.


By selecting the centipede spirit as your primary guardian, you will benefit from a significant passive ability that inflicts a debuff on your targets. This debuff reduces the damage they inflict by 2.5% and slows their movements by 10% for each stack, with a maximum of 8 stacks.


The centipede spirit comes equipped with numerous abilities that diminish your enemies' effectiveness while simultaneously dealing substantial damage over time, transforming them into mere puddles of green sludge.


Keep your health sustained by drawing life from enemies affected by your poisons through various skills and passive effects!


  • Withering Fist (Basic) : Quickly jab an enemy to inflict 5% damage and apply 30% poison damage over 6 seconds. Your third strike will explode on impact, damaging nearby foes and slowing them by 30% for 3 seconds.


  • Stinger (Core) : Deliver a strike in a small area, inflicting 70% damage to all enemies nearby, including those already poisoned.


  • Toxic Skin (Focus) : Passive ability that poisons enemies who attack you for 30% damage over 3 seconds. The active effect allows toxins to spill out, creating a poisonous trail while making you unhindered for 5 seconds.


  • Scourge (Defensive) : Summon a swarm of insects that bite enemies, inducing fear and slowing their movements for 3 seconds, while delivering 100% poisoning damage over 6 seconds.


  • Touch of Death (Potency) : Infect an enemy with a strike, dealing 5% damage and applying 300% poisoning damage over 9 seconds. When the infection ends or if the host is defeated, a swarm is released to seek out additional enemies for 9 seconds, dealing 10% damage per hit. You can have a maximum of 3 swarms active at any time.


Centipede Spirit Strategy

The ultimate ability, known as The Devourer, summons the centipede spirit, unleashing a line attack that deals a staggering 140% damage to foes while also spitting venom at additional targets for 40% damage. This powerful ability remains active for 15 seconds.


For those seeking more spiritborn builds, Mobalytics offers a wealth of resources!


A truly thrilling aspect of the spiritborn class is the variety of spirit guardians you can mix and match. One particularly intriguing combination is the centipede paired with the jaguar. By selecting centipede as your primary spirit guardian, you benefit from significant damage reduction. This allows you to focus on maximizing your damage per second (DPS) with the jaguar as your secondary spirit.


When jaguar is active, you will accumulate ferocity stacks with every enemy defeated or boss struck. Ferocity acts as a buff to your attack speed, enabling you to unleash a barrage of attacks that inflict substantial poison damage, effectively decimating your adversaries.


A standout synergy between these guardian spirits is the skill known as Touch of Death, a powerful poison damage-over-time ability that serves as an ideal opener. The excitement escalates when the poison effect comes to an end or the enemy is vanquished, triggering a Living Bomb effect.


This means that the poison detonates, affecting nearby enemies and spreading chaos among them. In scenarios where you find yourself surrounded by hordes of foes—something that frequently occurs—Touch of Death can propagate rapidly, inflicting poison across large groups of enemies.


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Effective Combat Strategies

Utilizing a powerful AOE clear strategy is essential.


Incorporating an explosive attack alongside a sweeping strike can significantly enhance damage against clusters of foes.


I’m excited to see how well this combination performs in action!


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Consider combining the centipede with the gorilla for a robust tank configuration.
The centipede provides significant damage reduction and healing,
but when paired with the gorilla, you gain enhanced barrier generation,
resolve, and crowd control.
If your goal is to become an unstoppable force,
this combination is one to explore.


A classic yet formidable option is to utilize two centipedes.
This setup focuses on maximizing poison damage,
along with powerful debuffs and impressive lifesteal.
The centipede stands out as a versatile spirit,
offering a great balance between offense and defense.
For those who appreciate a visually striking gameplay experience,
this configuration is definitely worth monitoring.


Check out our tier list to see how centipede spiritborn builds rank in the current meta and discover their strength this season!


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